Ito most likely "suffered a change in personality".
PFC or the prefrontal cortex is the cerebral cortex covering the front side of the frontal lobe. This cerebrum district has been embroiled in arranging complex psychological conduct, personality articulation, basic leadership, and directing social conduct. Harm to this part of the mind as Ito suffered, causes a lessened capability with regards to social feelings yet leaves logical thinking unharmed.