Answer:
The answer is D: Autoimmune damage to the synovium, desctruction of articular cartilage by pannus, and thickening of synovial fluid.
Explanation:
Osteoarthritis is the damage of the cartilage that is found in the joints of the long bones, which leads to its destruction, with decreased joint space, pain and inflammation. This friction that generates the damage, produces deformity and limitation for movements. It is a very common and frequent pathology.