Answer:His wife do need to tell him just to ensure he stops taking something that has no healing value on him.
placebo is given to a patient just to compare the defect of how it works but it has no healing value on someone so this bridges the doctor patient relationship.
This means he was given pills that he didn't even need just for the doctor to do his own test on these pills.
He should know so that he doesn't keep taking them because they are not helping him in anyway since they are just placebo.
