An adequate level of the protein _ is required to signal the _ to increase its production of gonadotropin-releasing hormone (GnRH) and initiate the process of puberty.

Gonadotropin hormones are the peptide hormones released by the nerve cells of the hypothalamus which stimulates the anterior hormone to release the gonadotropins like the LH and FSH hormones.

The GnRH hormone is released when the leptin, a protein hormone secreted by the adipocytes stimulates the GnRH neurons of the hypothalamus to release the hormone in both males and females.

Thus, leptin; hypothalamus is the correct answer.

An adequate level of the protein ___________ is required to signal the ___________ to increase its production of gonadotropin-releasing hormone (GnRH) and initiate the process of puberty.

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An adequate level of the protein _ is required to signal the _ to increase its production of gonadotropin-releasing hormone (GnRH) and initiate the process of puberty.