Answer:
1) 0.16 mg of pure heparin is in 80 Howell units
2) the loading dose, in mg of heparin for the 5-year-old boy is 2.618 mg
Step-by-step explanation:
Given that;
if a patient is less than 70 years of age then loading dose is 80 Howell units square per Kg of DM,
One Howell unit is equivalent to 0.0020 mg of pure heparin
1)
how many mg of pure heparin is in 80 Howell units.
that will be;
80 × 0.0020 = 0.16 mg
therefore 0.16 mg of pure heparin is in 80 Howell units
2)
First we find the dosing mass
so dosing mass = body weight of the 5year old boy × 90%
from the question his total body weight of 40 lbs and 1 kg = 2.20 lbs
so
dosing mass = 40lbs × 1kg/2.20lbs × 90/100
dosing mass(kg) = 16.37 kg
Now to calculate the Loading dose we say;
Loading dose = dosing mass × heparin required per kg
Loading dose = 16.36 kg × 0.16 mg heparin per 1kg
loading dose = 2.618 mg heparin
therefore the loading dose, in mg of heparin for the 5-year-old boy is 2.618 mg