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Increased temperature, such as from increased activity of skeletal muscle, causes the affinity of hemoglobin for oxygen to be reduced. Diseases such as sickle cell anemia and thalassemia decrease the blood's ability to deliver oxygen to tissues and its oxygen-carrying capacity.

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Some of the factors that decrease the passage of oxygen into the blood vessels are:

1. Carbon dioxide levels

2. Blood pH.

3. Increase in body temperature

4. Environmental factors.

5. Diseases.

Cardiac cycle can be defined as a complete heartbeat of the mammalian heart, which typically comprises sequential alternating contraction and relaxation of the atria and ventricles, therefore causing oxygenated blood to flow unidirectionally (one direction) throughout the human body.

On a related note, pulmonary circulation transports deoxygenated blood from the right side of the mammalian heart to the lungs, where blood picks up oxygen and returns to the left side of the mammalian heart.

Generally, some of the factors that decrease the passage of oxygen into the blood vessels are:

  • Carbon dioxide levels: increase in the level of carbon dioxide.
  • Blood pH: a decrease in the hydrogen ion concentration of the body.
  • Increase in body temperature.
  • Environmental factors: inhaling toxic chemicals.
  • Diseases: sickle cell anemia and thalassemia

Read more: https://brainly.com/question/24307064

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