jpw778 jpw778 04-03-2021 Biology contestada I will mark branlist What is the best description of the chromosomes by the end of metaphase of mitosis? The chromosomes reach opposite sides of the cell and begin to be incorporated into two new nuclei. The chromosome pairs collect in a line across the middle of the cell. The chromosomes separate at the centromere and begin to move apart. The chromosomes have coiled and become more compact.