answer: 100 sick people given tablets similar to Echinacea but with no herb
To test if a substance will have a certain effect we always need to have a group control. That group control should have the same size as the group that's going to take the drug, in this case, one hundred people. Another important thing that makes a group control is having them not take any treatment. Lastly, the control group should be representative of the same population, the "sick population" to serve as comparison to the treatment group.