Membranoproliferative glomerulonephritis type ii. This implies the correct answer is A.
Membranoproliferative glomerulonephritis is a type of kidney disease that affects the glomeruli of the kidney. This type of kidney disease can also be caused by other diseases such as hepatitis B or c, autoimmune disease, and hereditary diseases.
Membranoproliferative glomerulonephritis accounts for about 7% of the main renal that causes kidney damage in Adults and also accounts for about 4% in children.
membranoproliferative glomerulonephritis type ii is also known as dense deposits disease. Several cases of membranoproliferative glomerulonephritis type ii don’t show any pattern related to membranoproliferative but are linked with the malfunctioning of the alternate pathway of the complement system or alternative complement pathway.
Dense deposits disease is also associated with deposition of the complement C3 present in the glomeruli with no staining for immunoglobulin.
However, the presence of the complement C3 within the glomeruli without immunoglobulin shows that dense deposit disease can also be caused by uncontrolled AP activation.
In several cases, individuals with MPGN II can also develop drusen, which is caused by deposits within the innermost layer of the choroid, also known as Bruch's membrane under the pigmented layer of the retina of the eye.
Also, the other types of Membranoproliferative glomerulonephritis are type I and III, the type I are caused by the deposits of immune complexes with the kidney and type III are linked with complement receptor 6 deficiency.
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