There are choices for this question namely:
1. HMG-CoA reductase inhibitors
2. Fibric acid derivatives
3. Nicotinic acid
4. Colestipol
The correct answer is "HMG-CoA reductase inhibitors". These are well-known as "statins". Statins work by inhibiting the enzyme HMG-CoA reductase which is the rate limiting step of cholesterol synthesis. Without the enzyme, cholesterol synthesis will be halted and cholesterol levels will be inhibited. While statins do not have a direct action in the blood sugar of diabetic patients, diabetes predisposes the patients to hyperlipidemia and eventually atherosclerosis.
