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The resting membrane potential is dependent upon two important factors: 1) differences in sodium and potassium concentrations across the membrane (electrochemical gradients) and 2) differences in sodium and potassium membrane permeability. this activity will help you to review how the resting membrane potential of cells are generated and maintained. use the provided ions to correctly complete each sentence about the resting membrane potential. ions may be used more than once, or not at all.

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The membrane is more permeable to K+.

The resting membrane potential is maintained by Na ­K pumps that actively transport K+ into and Na+ out of the cell.

The concentration of K+ is higher inside than outside the cell.
The concentration of Na+ is higher outside than inside the cell.


All living cells have a membrane potential that varies depending on its cellular activities.

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