A patient was exposed to a nerve gas during a chemical warfare attack. The nerve gas inhibited the enzyme acetylcholinesterase. What will happen to the amount of acetylcholine in the synaptic cleft
When ACh is consistently released from the synaptic vesicles into the synaptic split, an expansion in transmitter fixation follows. The serine hydrolase AChE causes a fast hydrolysis of ACh with an exceptionally high response rate prompting the breakdown of ACh and its disposal from the synaptic separated
This response drastically diminishes the grouping of ACh inside the synaptic split. In this manner, ACh focus rots because of hydrolysis, dissemination and connection to AChR in an exponential fashion